Midfielder Phil Foden delivered in dramatic fashion, scoring in the first and 91st minutes, to seal Manchester City's 3-2 victory over Leeds United.
The win leaves United in 15th place in the Europa League standings on six points from four games.
Paris St Germain completed a domestic treble as they beat Olympique Lyonnais 6-5 on penalties to lift the French League Cup on Friday with the match ending in a 0-0 stalemate after regular and extra time. Second-half substitute Pablo Sarabia scored PSG's final penalty in the shootout after goalkeeper Keylor Navas had saved Bertrand Traore's spot kick to give the Ligue 1 champions and French Cup winners their ninth League Cup trophy.
England captain Wayne Rooney will be left out of the starting lineup for their last Euro 2016 Group B match against Slovakia.
Leicester City recorded the biggest ever English top-flight away win by beating 10-man Southampton 9-0 at a rain-sodden St Mary's to move up to second place in the Premier League on Friday.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
IMAGES from the English Premier League matches played on Saturday
Late goals by Mohamed Salah and Jordan Henderson earned Liverpool a crucial 3-1 victory at Southampton to move them back to the top of the Premier League on Friday.
News of all that's transpired on and off the football field
Photos from the English Premier League matches played on Saturday
Images from the EPL match played between Manchester United and Southampton on Monday.
Ronaldo's replacement Dybala scored in the 77th minute with a goal the Portuguese would have been proud of. After a quick exchange of passes, the Argentine twisted past Alessio Romagnoli and beat Gianluigi Donnarumma with a right foot shot.
Chelsea finally produced a performance befitting of champions to demolish Newcastle United 5-1.
A summary of Thursday's matches in Europe's second tier club football tournament
Inter Milan's aversion to Europa League football continued with a 3-1 defeat at Sparta Prague, while AS Roma ended a continental hoodoo stretching back seven games with a 4-0 home win over Romanian side FC Astra on Thursday.
Images from English Premier League matches played on Sunday.
Former Real youth player Joselu pulled a goal back for Alaves in the 59th minute, powering in a header from a free kick, but Benzema rounded off the victory for second-placed Real with an exquisite solo run and goal in the 70th minute.
Chelsea's third successive league win lifted them level on 18 points with Leicester City but are top thanks to a better goal difference. Leicester face Liverpool on Sunday.
Brighton and Hove Albion scored late to earn a 1-1 draw at Crystal Palace. Sheffield United and Fulham also drew 1-1 as both teams picked up their first points.
A summary of Tuesday's Group stage matches in the UEFA Champions League.
The injury to the Chile forward, who was left out of the squad for Tuesday's Champions League victory over Young Boys, "will require further investigation to confirm its severity", the club added.
Juventus raced into a 2-0 halftime lead after Napoli goalkeeper Alex Meret was sent off in the 25th minute. The visitors then had Pjanic dismissed and Napoli's Jose Callejon pulled one back before Insigne let the Turin side off the hook.
Schalke 04 hit back from two goals down to draw 2-2 and overcome fellow Germans Borussia Moenchenglach on away goals in their Europa League last 16 tie while Manchester United edged Rostov 1-0 to progress on Thursday.
Photos from the English Premier League matches played on Saturday
Images from the EPL matches played on Sunday
'The domination of American foreign policy by the military poses some hidden dangers for us.' 'We must factor in that the Pakistani military and the US military have close ties going back three generations.' 'Pakistan will find sympathetic ears in the Pentagon against India as the bogey man.' 'This will be further milked to the maximum by raising the ante in Kashmir through its proxies,' warns Colonel Anil A Athale.
La Liga leaders Barcelona handed Real Madrid more hope in the title race as they drew 0-0 at Athletic Bilbao on Sunday, only avoiding defeat thanks to some outstanding saves by Marc-Andre ter Stegen.
News of all that's transpired on and off the football field
Manchester City went 11 points clear with a record 14th consecutive Premier League win in an entertaining derby against Manchester United at Old Trafford.
News of all that's transpired on and off the football field
IMAGES from the English Premier League matches played on Saturday
